Clinical Trials for Triple Negative Metastatic Breast Cancer

Calendar Icon June 8, 2021
Reading Time Icon Read Time: 3 min
By Ciitizen

If you have been diagnosed with triple-negative metastatic breast cancer, coping with the stress is tough. According to the New England Journal of Medicine, “[t]riple-negative breast cancer is more common in younger women than in older women and in black persons than in persons of other races and ethnic groups, and it is often associated with visceral metastases.” It is also complicated and challenging to treat. There are many variables in the specific types of cell and cell receptors with this cancer. For example, according to the American Cancer Society, “in triple-negative breast cancer (TNBC), the cancer cells don’t have estrogen or progesterone receptors, nor do they make too much of the HER2 protein.”

It’s not easy to remain hopeful during this time, but it is essential to try. Even though triple-negative metastatic breast cancer is aggressive, researchers in the scientific community continue their relentless efforts to find a cure through clinical trials, as well as taking a closer look at better treatment options. Most recently, an article published in the American Journal of Cancer Research has found new information that may lead to more effective treatment: “We reviewed not only the FDA approved current treatment approaches but also presented a discourse addressing the possibilities for novel combination strategy that can induce tumor cell apoptosis, a critical cellular mechanism delaying/denying tumor progression.”

Clinical trials are essential for moving researchers toward finding a cure for cancer. In fact, because of clinical trials for triple-negative metastatic breast cancer, new treatments are being discovered. Gilead Sciences received approval at the end of last year for a new treatment called TRODELVY® (sacituzumab govitecan-hziy), which has been shown to triple overall progression survival rates versus chemotherapy alone. TRODELVY® is a Trop-2-directed antibody and topoisomerase inhibitor conjugate indicated for “the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease.”

If you have already had treatment and the cancer has returned, you may be asking yourself: what is the best way to find the clinical trials for triple-negative metastatic breast cancer that best fit you?

One option is to search for trials at But due to the complexity of this type of cancer, it is not an easy task. But there is a better way—you just need an advocate. Ciitizen is here to help.

The Ciitizen team believes that cures start with clinical trials. They want to help empower cancer patients with better health record management, which can help them find better treatment through the clinical trials for which they fit the criteria.

Ciitizen has the resources to help you through your journey, and the team is dedicated to getting patients what they need to find the best possible options for new and novel treatments that may be available through clinical trials. The goal is to do whatever they can to help eradicate breast cancer, including triple-negative metastatic breast cancer.

One of the most important factors in finding a clinical trial specifically for your type of cancer is having all your medical records in one place. Ciitizen has created a free service to privately maintain your medical records in a single secure location based on the principles of transparency, security, and control. Their mission is to empower you to have more control of your health data. This provides more options for your own care and helps advance research for others.

Ciitizen also has a free best-fit clinical trial matching program, which is based on your comprehensive treatment history. They have a team of advocates who can help you through the process.

Ciitizen is a free service that helps patients get more out of their health records. Our platform enables patients to find better treatment options and gives them the opportunity to advance the research for cures.

Ready to get your medical records in order? Get started today!

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